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10.1007/s00421-003-0833-3 3 AhtiainenJ

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doi:10.3390/ijms26072873

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However, recent evidence suggests that redox dysregulation may be an important or even primary trigger of a cascade of events leading to neurodegeneration

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Picture it as the lead guitarist in the body's band of antioxidants

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Quercetin-triggered Ca2+ signaling consists of both internal Ca2+ release and extracellular Ca2+ influx, and most importantly, quercetin-induced Ca2+ release from the ER, and as a result, inositol IP3R inhibition by xestospongin C blocked quercetin-induced Ca2+ release

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