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Allergy test before treatment and monitoring of blood anti-asparaginase antibodies level during treatment may also help to manage the complications caused by the use of L-asparaginase

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Maintenance and monitoring After the clearing and reinoculation phases, most clinicians move to a maintenance regimen , which may include low-dose antifungals (botanical or conventional), intermittent probiotic pulses, dietary moderation, and periodic check-ins

14 Researchers have investigated several ways to alleviate MTX-induced hepatotoxicity, including phosphodiesterase-4 (PDE4) inhibitors

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