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Zileuton, an anti-inflammatory compound, inhibits LOX5 and decreases -secretase, A, and tau after three months of treatment in a 3xTg mouse AD model ( Other inhibitors APP/PS1 mice treated with the iron chelator deferoxamine demonstrate reduced A and improved memory, but no significant improvement in cognition and memory is observed in AD patients (Ross and Siegel, 2021)

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The sensor fluorescence in the leaf epidermis was validated for all selected lines to show the characteristic cyto-nuclear pattern, a high signal-to-noise ratio when compared to the wild-type control, and clear separation of the biosensor fluorescence from chlorophyll autofluorescence