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Polyamines, such as spermine, spermidine, and their precursor putrescine, control fundamental biological processes, including transcription, translation, and cell signaling 24

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doi: 10.1523/JNEUROSCI.21-12-04183.2001

Therefore, it is critical to inhibit apoptosis of intestinal epithelial cells to prevent the intestinal pathologic conditions [86]

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