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Some practitioners employ intermediate dose increases, such as escalating by 0.25 mg increments rather than doubling doses, to improve tolerance in sensitive patients

Similarly, glucoraphanin-rich broccoli (400 g/week) consumed over a 12-week period was found to significantly reduce plasma LDL-C compared to consumption of standard broccoli in two randomized, double-blind parallel studies including 130 adults aged 50 years at risk of cardiovascular disease ( Neurological and Psychiatric Disorders Preclinical evidence suggests that glucosinolates and their metabolites, particularly sulforaphane, exhibit several biological properties that may be relevant to neurological and psychiatric conditions (Wu et al., 2016

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