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The severe deficiency of this enzyme results in a reduction of the NADPH generation, which results in a decrease in the production of hydrogen peroxide (H 2 O 2 ) and therefore the neutrophil microbicide activity is affected and likewise its inflammatory response 16

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Jun 2016;43(3):237-41

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Modeling monogenic diabetes using human ESCs reveals developmental and metabolic deficiencies caused by mutations in HNF1A

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