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Acetyl-L-carnitine Carnitine is an essential nutrient that is important for fatty acid transfer across the inner mitochondrial membrane, especially in hepatocytes

Conclusion: Our study supports previous reports of overestimation of hepatic steatosis with traditional methods and shows similar overestimation using Banff criteria

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We compared our candidate drugs to known anti-melanoma and NO-based drugs using publicly available drugs screens and high-throughput CRISPR data and experimentally validated six of these candidates in BRAF and NRAS mutated cell lines in mono and combination treatment with BRAF/MEK inhibitors