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When the measurement of radioactive iodine uptake is difficult, the measurement of anti-TSH receptor antibody and/or thyroid blood flow by ultrasonography may be useful to differentiate between destruction-induced thyrotoxicosis and Graves' thyrotoxicosis

MAPKAPK2 overexpression was associated with downregulation of KEAP1, increased Nrf2 nuclear accumulation, and elevated HO-1 protein levels

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This property makes Fe show a variable valency (e.g., Fe 2+ and Fe 3+ ) and the ability to form coordination units, such as Fe-S clusters