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In addition, the depletion of NMD factors, including Upf1, delays spontaneous differentiation to embryoid body (EB) formation, suggesting that NMD may be involved in the early stage of differentiation 15

Furthermore, during tumor proliferation, the UPS may influence various oncogenic signaling cascades, concurrently dysregulating multiple pathways and thereby complicating the development of targeted therapeutic strategies

Among the stage 3 comparisons for the sPLS-DA component 1 proteins, we also observed that one of the top-ranking proteins was Selenoprotein P (SELENOP), one of the few GPx3 interactors detected experimentally (Fig

Regulation of mTORC1 by PI3K signaling

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