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Optimization of sample preparation including change of matrix, matrix solvent composition, and matrix application methods did not help improve the sensitivity of the analysis

Our analysis revealed negative correlations between GLO-1 expression and several treatments, including omacetaxine, niclosamide, methotrexate, marinopyrole A, aporina, YM-155, STF-31, KX2-391, KPT185, GMX-1778, CAY-10618, and BI-2536 ( Figure 7 )

Oxidative Glutamate Toxicity In addition to the receptor-mediated excitotoxicity, an increase in extracellular glutamate can also lead to oxidative stress in the form of the non-receptor-mediated oxidative glutamate toxicity (Tan et al., 2001)