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Acknowledgements Research reported in this publication was supported by the International Fund for Congenital Adrenal Hyperplasia to G.D.H., F.B., and T.D., the Center for Cell Plasticity and Organ Design to T.D., the National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under Award Number R01DK043140, R01DK062027 to G.D.H

8 , e1002578 (2012)

This adaptation in tumor cells enhances their reliance on glutamine as a crucial source for biosynthesis, enabling them to effectively adapt to the hypoxic environment [100]