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However, their sensitivity warrants improvement, and their safety in patients needs further clarification

Some studies have shown that GSTP1 methylation can serve as a diagnostic tool for HCC with a sensitivity of approximately 50%75% and a specificity of 70%91% ( APC or SOCS (Liu et al., 2015), it can be used for early cancer detection in individuals who are genetically predisposed or exposed to carcinogens (Schnekenburger et al., 2014)

The protein level of significantly increased p16 was confirmed in keloid lesions and fibroblasts based on western blot analysis ( p = 0.0007, p = 0.03

doi: 10.1136/bmj.n71, 81 PalaszE.NiewiadomskiW.GasiorowskaA.WysockaA.StepniewskaA.NiewiadomskaG

Furthermore, OGT overexpression notably enhanced the expression of wild-type KGA (KGA-WT), while exhibiting no discernible effect on KGA-Thr563A, referred to as KGA-MUT (Fig