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As such, leptin, like many immune system mediators, functions as signaling molecules of both the immune and metabolic systems and is considered the cornerstone signal that links these two systems, as through which they regulate and influence each other (158)

While genetic, epigenetic, and molecular signaling mechanisms in EC physiology and pathophysiology have been extensively explored, the crucial role of EC metabolism in EC dysfunction and atherogenesis remains largely understudied

In clinical practice, Skinlite Cream may be used for managing hyperpigmentation, while Placentrex Gel is used to support skin healing and regeneration alongside antioxidant therapy

188 LCN2 inhibits ferroptosis by enhancing GPX4 and SLC7A11 expression and reducing intracellular iron levels, and LCN2 overexpression in colon cancer cells leads to resistance to 5-fluorouracil (5-FU) by inhibiting ferroptosis

Acute phase reaction and acute phase proteins