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Denervation of skeletal muscle after SCI can lead to mitochondrial toxicity (114), this leads to oxidative stress damage, mainly in the form of an imbalance between ROS production and detoxification (Figures 3, 4) (115, 116), so scavenging ROS and alleviating oxidative stress damage is an integral part of the treatment of skeletal muscle atrophy after SCI

Depending on the patient's history, we'll add fasting insulin, a thyroid panel, and inflammatory markers like hs-CRP

These circadian rhythms are regulated by the suprachiasmatic nucleus (SCN) of the hypothalamus

10.1016/j.freeradbiomed.2009.04.009 Free Radic

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