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doi: 10.1016/s0891-5849(00)00281-1

In contrast, an overdose of APAP causes hepatotoxicity by saturating the sulfation pathway and generating NAPQI that leads to a robust reaction between NAPQI and hepatic glutathione stores, which subsequently depletes glutathione (Xie et al., 2015)

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Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure

For one subject, the spectrum obtained at the second post-dose time point was of insufficient quality, and was omitted from analysis