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Kumar R, Herold JL, Schady D, Davis J, Kopetz S, Martinez-Moczygemba M, et al

10.1038/nrd3627 117 GaalA.GarayT

doi: 10.1038/s41430-019-0394-0 53 MondanelliGUgelSGrohmannUBronteV

The apparent promise of Ebselen in reducing SOD1 accumulation in vivo hints at the therapeutic potential of modulating posttranslational modification of SOD1 protein to counteract SOD1 misfolding, suggesting a greater research focus be paid towards developing similar treatment strategies