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FP, correlation between HIF expression and favorable prognosis a HIF2 expression in macrophages b Correlation using mRNA levels c Correlation of HIF1 expression with favorable prognosis d Correlation with cytoplasmic HIF2 expression The observations summarized in Table 1 have led to the general view that elevated HIF protein expression in tumor cells, whether induced by hypoxia or aberrant oncogenic signaling, actively drives tumor growth and progression by regulating the expression of critical target genes

FDA approval: AOD-9604 is not approved

Hildesheim and New York: Georg Olms, 1977

Severe side affects are rare, though they may occur

Results showed that forskolin supplementation both helped glucose metabolism and lowered body fat in the high-fat diet-fed mice