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Figure 3 Several studies suggest that Th1 and T helper 17 (Th17) cell differentiation are specifically regulated by mTORC1 signaling, whereas Th2 cell differentiation depends on mTOR complex 2 (mTORC2) signaling (68, 70, 71)

Single-cell sequencing of pneumonia, sepsis, and sepsis with ARDS found that the monocyte cluster in patients with early ARDS caused by sepsis was characterized by down-regulation of SOCS3 expression and up-regulation of multiple type I IFN-induced genes (194)

This continuous bombardment by mycotoxins keeps mast cells in a chronic state of hyper-reactivity