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Tuttle KR, Agarwal R, Alpers CE, et al

The combined regimen (72) had an ORR of 65%, a median time to disease progression (mTTP) of 8.3 months, and an mOS of 12.3 months

Above the high-risk line (300 ug/mL at 4 hours) indicates a high risk of liver failure (massive ingestion), which may warrant even more aggressive therapy (discussed below)