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NF-B and ER stress in advanced atherosclerosis During the last decades, people have been trying to understand the pathophysiology of atherosclerosis, though the precise mechanisms underlying plaque destabilization still remain unclear

( b ) Representative flow cytometry plot showing Ly6C versus CD146 staining in the PDPN MAdCAM-1 CD157 fraction of C57BL/6 FRCs

[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Chen Q., Espey M.G., Sun A.Y., Pooput C., Kirk K.L., Krishna M.C., Khosh D.B., Drisko J., Levine M

C.et al (2008)

In a study utilizing a neonatal mouse model of hypoxicischemic brain injury, it was demonstrated that hydrogen activates the Nrf2 pathway to enhance intracellular antioxidant defenses, effectively clearing excess ROS