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Given these transcriptional changes, we next explored the potential impact on lipid composition through lipidomic profiling of erastin-treated CAOV3 cells upon exposure to ascites

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3 When the endothelium is damaged, the von Willebrand factor (vWF) in the vascular epithelium interacts with the glycoprotein 1b receptors on the platelets surface, resulting in their activation and adhesion to the exposed collagen fibers within the vascular wall