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The EMSA results indicated that the purified CopRHis 6 bound to biotin-labeled copB probes, and retarded their mobility ( Figure 6B )

In a comparative bioinformatics analysis of endometriosis and ovarian cancer, the immunohistochemical staining analysis further substantiated a robust association between elevated AIM2 expression and heightened Ki-67 activity in clinical samples of EAOC

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They bind to sperm surface proteins to reduce damage from enzymes and reactive oxygen species

However, this co-staining assay revealed no significant differences in RSL3-induced cell death rates between the control, WT, R62D, and S14C groups (Figures 2F,G), suggesting that nuclear F-actin assembly could be a concurrent feature rather than a determinant of ferroptotic sensitivity