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Orientation-specific attachment of polymeric microtubes on cell surfaces

This contains two proteins 'Coronatine Insensitive 1 or COI1' and 'Jasmonate ZIM-domain or JAZ', with the latter acting to repress transcription, and this complex is stabilized cooperatively by JA-Ile, which has been termed a 'molecular glue', and inositol pentakisphosphate (IP5)

All the authors contributed to the study and approved the manuscript for publication

Normal saline, Hams F10 medium and L-carnitine working solution were prewarmed in 37 constant temperature water bathing for 5 min before use

Research in cell and animal models demonstrates its capacity to suppress NF-kB activation, reduce pro-inflammatory cytokine release including IL-1b, TNF-alpha, and IL-6, and interact with melanocortin receptors on immune and intestinal epithelial cells