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55 56 Thats why other supplements are often used to raise glutathione more effectively: N-acetyl cysteine (NAC)

Increasing amounts of NADPH (1250 M) were subsequently added to the wells and the solutions were imaged on an LSM880 confocal laser scanning microscope (Carl Zeiss AG, Oberkochen, Germany) with a 63x immersion objective (LD LCI Plan-Apochromat 63x/1.2 Imm Corr DIC M27) using a 440 nm pulsed excitation laser (LDH-D-C-440, 40 MHz repetition rate) managed by a PicoQuant FLIM module (Sepia PDL828-S, PMA Hybrid 40, MultiHarp 150 4N, Time Harp 260 PICO Dual) (PicoQuant, Berlin, Germany)

120 , 146156 (2017) Z

The ongoing degradation of NRF2 ensures that only the basal expression levels of NRF2 target genes are maintained, supporting essential housekeeping functions

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