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In cis signaling, IL-6 forms a complex with the membrane-bound IL-6 receptor (mIL-6R) and gp130 which then activates downstream the Janus kinases 1 (JAK1) and signal transducer and activator of transcription 3 (STAT3)

It protects neurons from oxidative damage, supports mitochondrial function, and may reduce the risk of neurodegenerative diseases such as Alzheimers and Parkinsons

Martinotti G, Reina D, Di Nicola M, Andreoli S, Tedeschi D, Ortolani I, Pozzi G, Iannoni E, D'Iddio S, Janiri L

Gh_A12G2084 and Gh_D12G2260 were found to have high homology with CotAD_39521, when the protein sequence of CotAD_39521 was used for a Blast search with another genome database of the G

Cells 12, (2023), Abstract Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells: S.W