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Epithalon peptide experimentation appeared to have led to an upregulation of neurogenic differentiation markers, including Nestin, GAP43, Tubulin III, and Doublecortin, in hGMSCs

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10.1053/j.gastro.2019.01.252 Gastroenterology 77 LiJ.LiuL.LiuX.XuP.HuQ.YuY

Through the presence of VEGFR 2 receptors as a growth factor, growth hormone receptors, VEGFR2-AKT-eNOS, ERK , FAK-paxillin, FoxO3a, p-AKT, p-mTOR, and p-GSK-3 pathways, and characteristic loops, the level of pro-inflammatory cytokines is reduced, thereby exhibiting protective effects in the event of inflammation throughout the digestive system