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Mounjaro contains a single active pharmaceutical ingredient: tirzepatide , a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

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It is also generally not advised to be taken while breastfeeding, as studies about whether it passes into breast milk are inconclusive

Originally characterized at the University of Florida by the Stephen ORahilly and Robert Kraft groups, the compound has been studied in preclinical research for body composition, adipose tissue lipolysis, glucose homeostasis, skeletal muscle aging, and metabolic disease endpoints

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