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doi: 10.1080/14737175.2021.1968298 79

Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) improved endothelial function in Zucker diabetic fatty rats and in db/db mice [49]

The limited, short-term efficacy of GCs, coupled with their significant contraindications and non-response rates, creates a profound unmet need for safer and effective therapeutic alternatives