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These sex-related differences in plasma lipoproteins start to be evident during puberty, in concomitance with the increase in testosterone in males and estrogens in females (Figure 1) ( Estrogens increased ApoA-I expression in the liver and HDL-C levels in pre-menopausal women by modulating the expression of SR-BI and hepatic lipase (Figure 1) ( Differences in lipid profile have also been associated with sex-specific gene expression profile

Abstract Affective disorders such as major depression and bipolar disorder are among the most prevalent forms of mental illness and their etiologies involve complex interactions between genetic and environmental risk factors

The role of DNA methylation and histone modifications in the pathogenesis of hematological malignancies and solid cancers: mechanisms, clinical implications, and therapeutic potential

2008a;62(10):1547-1559

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