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AGEs and Alzheimers disease Various forms of AGEs are markedly aggregated in neuronal plaques in the brain as well as in the serum and cerebrospinal fluid (CSF) in experimental models and autopsied brains from AD patients compared with the corresponding controls

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QUIN acts as a potent redox cycler and a direct inhibitor of the mitochondrial electron transport chain (ETC), particularly at complexes I and II (Zhao et al., 2019)

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