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Collectively, these changes can result in the cells demonstrating the senescence-associated secretory phenotype (SASP), which results in the cell altering its secretions to promote senescence in its neighbors and inflammation in tissues 53,186

Cells were incubated with pan-DC MicroBeads for 15 min at 4 C and, after washing, cells were applied to LS magnetic-activated cell sorting columns in a magnetic field

Aptamers, smaller than antibodies, minimal toxicity, and scalability of production, overcome physiological barriers like blood-brain barriers, enhancing therapeutic treatments and gaining access to underdeveloped nations, making them useful for biodefense and accessing underdeveloped nations (64) The pros and cons of antibody and aptamer are tabulated in Table 1

Its selectivity profile makes it a valuable tool compound for dissecting the ghrelin/GHS axis in endocrine research settings

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