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In animal studies, five-week oral administration of HSD in rat PD models significantly improved performance in rotarod and spontaneous movement tests

Funding The authors would like to acknowledge the University Grants Commission (UGC) and Department of Science and Technology (DST) for providing financial assistance under the Special Assistance Programme-II (SAP-II) and FIST Programme respectively to the Department of Pharmaceutics, SPER, Jamia Hamdard

Penetrance studies concerning the VPS35 p.D620N mutation indicate that 25% of carriers exhibit PD symptoms by the age of 45 or younger, with a median onset age of 49 years, and 75% of individuals showing symptoms by age 59 or older

Another widely used toxin is 6-OHDA that requires direct injection into the brain as it does not efficiently cross the bloodbrain barrier

In this article, well discuss the cellular functions of glutathione, its different forms, and its applications in scientific research