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Cell 20 , 329341 (2011)

A phase II multicentre randomized trial (ABC-07) included patients with locally advanced CCA (46% pCCA, 39% dCCA, 14% iCCA) 277

Flavonoids can modulate the NF-B pathway through multiple mechanisms, thereby reducing the production of pro-inflammatory factors

Although genetic factors have been implicated as contributing to a substantial proportion of ASD risk, a range of other environmental exposures have also recently been identified as potentially contributing to a heightened risk of developing ASD across the lifespan