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Controlled Document Ref: 1001(a) Issue: 3 Approval Date: April 2011 Expiry Date: October 2011 YOU MUST BE AUTHORISED BY NAME, UNDER THE CURRENT VERSION OF THIS PGD BEFORE YOU ATTEMPT TO WORK ACCORDING TO IT Patient Group Direction for Ambulance Paramedics and Nurses PGD NAME - DICLOFENAC INJECTION POM Indication Inclusion criteria Exclusion criteria Cautions/Need for further advice Action if patient declines or is excluded CLINICAL CONDITION Pain and inflammation associated with acute musculo-skeletal disorders, acute gout or arthritic conditions

[DOI] [PubMed] [Google Scholar] 352.Wang, L., Chen, C., Zhou, H., Tao, L

NNMT inhibition reduces one methylation pathway, but it doesn't directly deplete systemic methyl donorsit redirects nicotinamide away from methylation toward NAD+ salvage

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