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[PubMed: 12850279] 35

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The groups most likely to develop B12-related hair and skin changes are the same ones at risk for deficiency generally: vegans and vegetarians, adults over 50, people on long-term metformin or proton pump inhibitors, anyone who's had bariatric surgery, and people on GLP-1 protocols whose reduced appetite has significantly lowered their overall nutrient intake for an extended period

Support Metabolism and Weight Management In cases of B12 deficiency, supplementation can help regulate metabolism, contributing to better energy conversion and even mild weight loss