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Three days later, mice received oral gavage of metformin at 150 mg/kg followed by injection of STF-31

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Additionally, a high-fat diet can accelerate the progression of malignant tumors, whereas intermittent fasting or caloric restriction can increase the proportion of effector T cells in the TME, thereby enhancing antitumor immunity [402, 403]

ZR2024MH134), the Science and Technology Innovation Project of Yantai (Grant No

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