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They're not just about addressing deficiency

The original law was intended to make it easier for similar drugs to get FDA approval, but by removing the statement about chemically synthesized polypeptides at the 11th hour, it disenfranchised thousands of people from getting the medication they need

Understanding the cellular phenotype and heterogeneity of cancers prior to the initiation of cancer treatment is critical, as is monitoring response to therapy during its course [98]