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ANDRADE, M.M

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*Correspondence: Lei Xu, [email protected] Liu, [email protected] These authors have contributed equally to this work This article was submitted to Cellular Neuropathology, a section of the journal Frontiers in Cellular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In a chemical-induced colitis mouse model, researchers observed an increase in the cyclooxygenase-2 (COX-2) and glial fibrillary acidic protein within the hippocampus and the hypothalamus and a reduction in COX-2 and brain-derived neurotrophic factor in the amygdala [12]

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner