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He hypothesized that because coagulation factors II, VII, VIII, and IX and platelet function are damaged directly by the sclerosing solution, coagulation at the injection site is delayed

Instead, they recommended methylcobalamin, a form of B12 where a methyl group replaces the cyano group

In a follow-up study published in Molecules in 2014, Chang explored how BPC-157 interacts with the growth hormone receptor (GHR) in tendon fibroblasts