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The NLRP3 inflammasome signaling pathway Inflammasomes are a group of intracellular multimeric protein complexes that are formed by germline-encoded pattern-recognition receptors (PRRs) [31]

10.3390/ijms20205211 120 PharaohG.KamatV.KannanS.StuppardR

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Genetic causes of migraines include: Gene changes that can predispose you to certain health conditions, such as migraines Aura symptoms, such as flashes of light, blind spots, zigzag lines, numbness, speech problems, and muscle weakness A family history of migraines, which is the case of familial hemiplegic migraines Sporadic hemiplegic migraine, which means youre the first person in your family with hemiplegic migraines After your diagnosis of hemiplegic migraines, the team at the Advanced Headache Center conducts tests to identify the patterns of your migraine attacks

It is present in human plasma, saliva, and urine