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Description

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

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Bai YT, Chang R, Wang H, Xiao FJ, Ge RL, Wang LS

Oxidative deamidation is the most common chemical degradation process of mAb, which may result in changes in their physical properties such as hydrophobicity, charge, secondary and/or tertiary structure, and lower thermodynamic or kinetic barriers to unfolding