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A decrease in GS activity alone without a change in GCL and a fall in GSH levels occurred after surgical trauma in human skeletal muscle [50]

Generally, Group I mGluRs carry activating G s or G 11 subunits, are localized postsynaptically, and lead to cell depolarization and increased neuronal excitability

Anthranilate is then phosphoribosylated to form N -(5-phosphoribosyl)-anthranilate (PRA), in a reaction catalyzed by anthranilate phosphoribosyltransferase (EC 2.4.2.18)