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People with compromised immune systems, chronic respiratory conditions, or genetic susceptibilities are particularly vulnerable

While direct evidence from silicosis models is still needed, this mechanistic insight suggests that targeting ferroptosis via stem cell paracrine signaling could represent a promising therapeutic approach against silica-induced pulmonary fibrosis

Modulating Dnmt3a or Tet2 expression has shown potential in reversing age-related memory impairments (166).Tau proteins, essential in AD DNA methylation, are instrumental in regulating genes linked to A and tau pathways (167)

ASD phenotypes (social-communication impairments and restricted, repetitive patterns of behavior) are commonly associated with intellectual disabilities, anxiety, depression, epilepsy, attention deficit hyperactivity disorder (ADHD), sleep disorders, dyspraxia, and lack of verbal communication [40]