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Shikonin and cisplatin synergistically overcome cisplatin resistance of ovarian cancer by inducing ferroptosis via upregulation of HMOX1 to promote Fe(2+) accumulation

Vitamin B12 can be converted to coenzyme B12 in tissues, and as such is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine, a reaction which also requires folate

In contrast, GPX4 deficiency is associated with the course of several RCDs, especially ferroptosis, which will be covered in the following sections (Figure 5)

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins

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