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Conclusion: Our findings suggest that LSEC HSPA12B is required for maintaining the unique phenotype and function of LSECs, which are essential for hepatic Kupffer cell periportal zonation and bacterial clearance during sepsis

10.1007/s13659-020-00293-7 11 JastrzbA.Jarocka-KarpowiczI.SkrzydlewskaE

While various studies have focused on the beneficial effects of prebiotics, probiotics, and synbiotics individually, few studies have been published on the combined effects of prebiotics and probiotics