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iScience 24 , 102374 (2021)

doi: 10.3389/fimmu.2018.01873

In Phase 2 trials (the TRIUMPH-2 study involving 338 participants over 48 weeks), the 12 mg dose of Retatrutide produced an average weight loss of 24.2%

Enforcement actions happen, but they are typically against local sellers who have crossed specific advertising lines, and they do not affect the underlying supply chain (Chinese manufacturing, e-commerce listings, telehealth clinics in permissive jurisdictions)