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Mech Ageing Dev 217:111888

HIF-1 and HIF-2 differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

The targeted delivery of intracellular copper relies on multiple metallochaperone systems:(a) Cytochrome c oxidase copper chaperone COX17 (Cox17) transports copper to mitochondria and participates in cytochrome c oxidase assembly (Amaravadi et al., 1997)