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The first five subjects who volunteered for the histological evaluation underwent pre- and post-treatment biopsies

This is equivalent to about 7 standard drinks for men and 5 standard drinks for women

What they found (summary): NAD+ is the integrator of metabolic and stress signals The decline in NAD+ with age is a causal factor , not merely a correlation PARP and CD38 are the main consumers of NAD+ in aging cells Selective CD38 inhibitors are a new therapeutic option NAD+ has potential in neurodegeneration (Alzheimers, Parkinsons, ALS) Why it matters: Verdins review in Science gave the NAD+ field academic prestige

It speeds up the healing process and repairs the skin barrier

Over-dosed: This is the more concerning scenario