glutathione peroxidase deficiency anemia Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders Glutathione Peroxidase: An Antioxidant Enzyme

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Glutathione is generally well tolerated, but in some people, it can cause mild gastrointestinal distress and allergic reactions if given in very high doses or by way of IV use

A recent study reported that Hmox1 activation induces heme accumulation and drives cardiomyopathy through ferroptosis induction, whereas inhibition of Hmox1 reduced cardiac damage in SCD 46

Amino Acids (this issue) Diwakar L, Ravindranath V (2007) Inhibition of cystathionine--lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS