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Initial western blot (WB) analysis of PSMA high 22Rv1 cells demonstrated that, compared with PBS controls, Psa-AR achieved 79% AR degradation, representing a 45% enhancement over P-AR

In this context, the observed reduction in RONS levels, suppression of iNOS expression, and activation of the Nrf2/ARE pathway suggests that VACV actively promotes an antioxidant state early during infection

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Protein Cell 6 , 254264 (2015)

The cytokine-mediated inflammatory process, oxidative stress, and changes in the induction of apoptosis predispose the elderly to chronic disease